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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHMP2A All Species: 28.48
Human Site: S184 Identified Species: 48.21
UniProt: O43633 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43633 NP_055268.1 222 25104 S184 D E L S N L P S T G G S L S V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_533565 222 25144 S184 D E L S N L P S T G G S L S V
Cat Felis silvestris
Mouse Mus musculus Q9DB34 222 25115 S184 D E L S N L P S T G G S L S V
Rat Rattus norvegicus Q8CGS4 223 25043 T185 G K A P S K V T D A L P E P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q5ZHN1 220 24714 P184 D E L A T L P P P G G S L A A
Frog Xenopus laevis Q6IP52 220 24996 S184 D E L S N L P S T G G S L S V
Zebra Danio Brachydanio rerio Q7ZW25 220 25089 A184 D E L S N L P A T G G S L S V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_651455 256 27330 S184 E Q L G D L P S A S G S L S I
Honey Bee Apis mellifera XP_625164 227 25773 Q184 D Q L S G L P Q A S G S L S V
Nematode Worm Caenorhab. elegans NP_496717 237 25954 S184 E E M A G L P S A A G G L N A
Sea Urchin Strong. purpuratus XP_780405 222 25135 S184 D D L V G I P S T G G A L N T
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001132529 223 25018 S184 Q E L V G A P S A A V A Q P A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SKI2 225 25274 S185 Q E L V N A P S G A V A V P A
Baker's Yeast Sacchar. cerevisiae P36108 232 26272 Q188 S Q L Q S T P Q N L V S N A P
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 99 N.A. 99.5 25.1 N.A. N.A. 88.2 91.8 89.6 N.A. 66 73.5 65.4 69.8
Protein Similarity: 100 N.A. N.A. 99 N.A. 99.5 52.9 N.A. N.A. 93.2 95.9 95.5 N.A. 78.5 85.9 80.1 86.9
P-Site Identity: 100 N.A. N.A. 100 N.A. 100 0 N.A. N.A. 60 100 93.3 N.A. 53.3 66.6 40 53.3
P-Site Similarity: 100 N.A. N.A. 100 N.A. 100 20 N.A. N.A. 73.3 100 100 N.A. 80 73.3 66.6 80
Percent
Protein Identity: N.A. 55.1 N.A. 55.1 43.5 N.A.
Protein Similarity: N.A. 74.4 N.A. 75.5 69.4 N.A.
P-Site Identity: N.A. 26.6 N.A. 33.3 20 N.A.
P-Site Similarity: N.A. 33.3 N.A. 46.6 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 15 0 15 0 8 29 29 0 22 0 15 29 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 58 8 0 0 8 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 15 65 0 0 0 0 0 0 0 0 0 0 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 8 29 0 0 0 8 50 72 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % I
% Lys: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 86 0 0 65 0 0 0 8 8 0 72 0 0 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 43 0 0 0 8 0 0 0 8 15 0 % N
% Pro: 0 0 0 8 0 0 93 8 8 0 0 8 0 22 8 % P
% Gln: 15 22 0 8 0 0 0 15 0 0 0 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 8 0 0 43 15 0 0 65 0 15 0 65 0 50 0 % S
% Thr: 0 0 0 0 8 8 0 8 43 0 0 0 0 0 8 % T
% Val: 0 0 0 22 0 0 8 0 0 0 22 0 8 0 43 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _